The term 'Virus in 'The Hot Zone'' is referring to the Ebola virus, which is a highly contagious and deadly virus that was first discovered in 1976 near the Ebola River in what is now the Democratic Republic of Congo. It is spread through contact with bodily fluids and can cause severe bleeding, organ failure, and death. The virus has been featured in the 1994 book 'The Hot Zone' by Richard Preston, which details the outbreak of the virus in Reston, Virginia in 1989.