The term SIGN OF STRESS can be broken down into six crossword solutions: ACCENT (6 letters), UNDERSCORE (10 letters), ITALICS (7 letters), TALICS (6 letters), TIC (3 letters), and ACUTEACCENT (11 letters). ACCENT is a term used to describe a change in the pitch or tone of a person's voice, often used to emphasize certain words. An UNDERSCORE is a line drawn beneath a word or phrase to indicate emphasis. Italics is a type of font that slants to the right and is often used to emphasize certain words. Talics is a misspelling of italics. TIC is an abbreviation for a spasm or twitch, often associated with STRESS. Acute ACCENT is a diacritical mark used to indicate STRESS or a change in pronunciation.