The term 'MADDENS' can be broken down into five different crossword solutions: IRES (4 letters), ENRAGES (7 letters), IRKS (4 letters), GALLS (5 letters), and DERANGES (8 letters). IRES means to become angry or irritated, ENRAGES means to make extremely angry, IRKS means to annoy or irritate, GALLS means to outrage or insult, and DERANGES means to disturb the order of. All of these words are related to the idea of anger, annoyance, and irritation, which is what the term 'MADDENS' implies.