The term 'Wife of Muhammad' can be summarized by two crossword solutions: Aisha (5 letters) and Ayesha (6 letters). Aisha was the third and favorite wife of the Islamic prophet Muhammad. She was the daughter of Abu Bakr, Muhammad's closest companion. Ayesha was also a wife of Muhammad and is sometimes referred to as the Mother of the Believers. She was the youngest wife of Muhammad and is known for her knowledge and wisdom.