The term WHOLE WORLD IN HIS HANDS is a phrase that is often used to describe someone who has a great deal of power or influence. It is derived from the Bible verse Psalm 95:4, which states 'IN his HANDS are the depths of the earth; the heights of the mountains are his also.' This phrase is often used to refer to God, but it can also be used to describe a person who has a great deal of control over the world. The crossword solution for this phrase is HIS, which is an abbreviation for His or He.