The answer to the crossword clue 'Where Regulus is' is LEO, which is an acronym for the constellation of LEO. LEO is one of the 88 modern constellations and is located in the northern sky. It is the fifth largest constellation in the sky and is visible throughout the year in most of the northern hemisphere. Regulus is the brightest star in the constellation of LEO and is located at the bottom of the sickle-shaped pattern of stars that make up the constellation.