Western New York County is a region in the state of New York, located in the western part of the state. The two counties that make up this region are Erie and NIAGARA. Erie County is the most populous county in the region, with a population of over 921, 000 people. NIAGARA County is the second most populous county in the region, with a population of over 216, 000 people. Both counties are home to many cities, towns, and villages, and are known for their beautiful landscapes and rich history.