Wednesday's Child is a proverb that dates back to the 16th century. It states that Wednesday's child is full of WOE, meaning that children born on Wednesdays are often unlucky or have difficult lives. The proverb has been adapted over time and is now used to refer to any person who has had a difficult life. The crossword solution for the term 'Wednesday's Child is Full of ___' is WOE, which is a three letter word meaning sorrow or grief.