Wean is a term used to describe the process of gradually introducing an infant or young animal to solid food and reducing its dependence on milk. The two crossword solutions for this term are 'ALIENATE' and 'ESTRANGE', both of which have 8 letters. ALIENATE means to cause someone to become unsympathetic or hostile, while ESTRANGE means to cause someone to become distant or unfriendly. Both words can be used to describe the process of weaning, as it involves gradually reducing the bond between the infant and its mother.