Alienate is a term used to describe the act of causing someone to become unfriendly or unsympathetic. DISAFFECT, which has nine letters, means to cause someone to lose affection or loyalty. ANTAGONIZE, with ten letters, means to provoke hostility or opposition in someone. WEAN, with four letters, means to gradually deprive someone of something they are attached to. DIVORCE, with seven letters, means to legally end a marriage. Separate, with eight letters, means to keep apart or DIVIDE. DISGUST, with seven letters, means to cause revulsion or strong disapproval. DISSOCIATE, with ten letters, means to separate oneself from a group or idea. SOUR, with four letters, means to make something unpleasant or hostile. REPEL, with five letters, means to drive away or cause aversion. DIVIDE, with six letters, means to separate into parts or groups. DISUNITE, with eight letters, means to cause people to be divided or estranged. EMBITTER, with eight letters, means to make someone feel resentful or angry. ESTRANGE, with eight letters, means to cause someone to become distant or unfriendly.