Up in Smoke is a phrase that is often used to describe something that has been destroyed or ruined. It can also be used to describe something that has been consumed quickly or completely. The crossword solutions for this phrase are PFFT (4 letters), AFLAME (6 letters), and GONE (4 letters). PFFT is an onomatopoeia that is used to describe a sound made when something is extinguished quickly, such as a flame. AFLAME is an adjective that means burning or blazing. GONE is an adjective that means no longer present or existing. Together, these three words provide a vivid description of something that has been destroyed or ruined.