TV's Winfrey is a reference to the famous talk show host, OPRAH Winfrey. Winfrey is best known for her long-running talk show, The OPRAH Winfrey Show, which aired from 1986 to 2011. She has also been involved in numerous other projects, including acting, producing, and philanthropy. Winfrey is one of the most influential people in the world and has been credited with helping to shape American culture.