The crossword solution for the term SUFFIX WITH SERPENT is 'INE', which is a three letter suffix. This suffix is derived from the Latin word 'inus' and is often used to denote something related to snakes or serpents. It is commonly used in scientific names of species, such as the genus Thamnophis, which is a type of garter snake. In addition, it is also used in some medical terms, such as ophidiopathy, which is an inflammation of the nerves caused by a snake bite.