The crossword solution for the term SUFFIX WITH DEPEND OR DIFFER is ENCE, which is a four-letter word. ENCE is a suffix that is commonly used to form nouns from verbs. It is often used in words that describe a state of being dependent or different from something else. For example, the word 'DIFFERENCE' is formed by adding the suffix ENCE to the verb 'DIFFER'. Similarly, the word 'DEPENDENCE' is formed by adding the suffix ENCE to the verb 'DEPEND'.