The crossword solution for the term 'Stupefy with drink' is BESOT, which is a five-letter word. BESOT is an archaic verb meaning to make someone drunk or to stupefy them with alcohol. It is derived from the Middle English word besotten, which means to make drunk or to befuddle. The term is still used in some parts of the United Kingdom and is often used in literature to describe someone who has been made drunk or confused by alcohol.