The answer to the crossword for the term 'State North of Missouri' is Iowa, which is a four-letter word. Iowa is a state located in the Midwestern United States, bordered by the Mississippi River to the east and the Missouri River to the west. It is the only state whose east and west borders are formed entirely by rivers. Iowa is the 29th most populous and the 30th most extensive of the 50 U.S. states. It is known as the Hawkeye State, named after the Iowa Native American tribe.