The crossword solution for the term SOUTHWESTERN CITY is PHOENIX, a 7-letter word. PHOENIX is the capital and most populous city of the U.S. state of Arizona. It is also the fifth most populous city in the United States, with a population of over 1.6 million people. PHOENIX is located in the southwestern region of the United States, in the Sonoran Desert. It is known for its hot, dry climate and its many cultural attractions, including museums, galleries, and performing arts venues.