The Peedee and Santee Rivers are two major rivers in South Carolina. The Peedee River, also known as the Great Pee Dee River, is a long river that originates in the Appalachian Mountains and flows through North and South Carolina before emptying into Winyah Bay. The Santee River is a shorter river that begins in the Sandhills region of South Carolina and flows eastward to the Atlantic Ocean. Both rivers are important sources of water for the state and provide recreational opportunities for fishing and boating.