The term 'South American Lizard' can be summarized by two crossword solutions: IGUANA (6 letters) and Tegu (4 letters). Iguanas are a type of lizard native to Central and South America, and they are known for their long tails and spiny crests. Tegus are also native to South America, and they are large lizards that can grow up to four feet in length. Both iguanas and tegus are popular pets due to their docile nature and attractive appearance.