The term 'SITE OF A 16TH-CENTURY COUNCIL' is solved by the crossword answer 'Trent' (5 letters). Trent is a city in northern Italy that was the site of the Council of Trent, a 16th-century Roman Catholic Church council. The council was held between 1545 and 1563 and was convened to address the challenges posed by the Protestant Reformation. It was one of the most important councils in the history of the Catholic Church and resulted in the codification of Catholic doctrine and the establishment of the Roman Inquisition.