A shout of pain is an expression of intense suffering or anguish. It is usually a loud, sudden exclamation that is often accompanied by physical gestures. The two crossword solutions for this term are YOWEE (5 letters) and YOW (3 letters). YOWEE is an informal interjection used to express surprise, shock, or pain, while YOW is an informal interjection used to express pain or distress. Both words are typically used in situations where someone has experienced a sudden, unexpected pain or shock.