The crossword solution for the term SCRAPE, AS THE KNEE is SKIN. SKIN is the outermost layer of the body and is composed of two layers: the epidermis and the dermis. It serves as a protective barrier against environmental factors such as bacteria, viruses, and other pathogens. It also helps regulate body temperature and provides a waterproof barrier. SKIN is the largest organ in the body and is made up of millions of cells.