The crossword solution for the term SCI-FI MOVIE CREATURE is BLOB, which is a four letter word. A BLOB is a type of creature that has been featured in many science fiction movies. It is usually depicted as an amorphous, gelatinous mass with no definite shape or form. Blobs are often portrayed as dangerous and hostile creatures that can consume anything in their path. They are also known to have some form of intelligence, making them even more dangerous.