The crossword solution for the term SAN ___: TEXAS CITY NICKNAME is 'ANTONE' (6 letters). San Antonio, Texas is often referred to as 'San Antone' or 'San Tone' by locals. This nickname is derived from the city's full name, San Antonio. The city is the second most populous in Texas and the seventh most populous in the United States. It is known for its Spanish colonial missions, the Alamo, and River Walk.