The crossword solution for the term SAMOS SITE OF ANCIENT is IONIA, which is a region in western Anatolia in present-day Turkey. It was an ancient Greek region and was home to several important cities, including Ephesus and Miletus. Samos was one of the most prominent cities in Ionia, and it was known for its rich cultural heritage and its many temples and monuments. It was also the site of the famous Temple of Hera, which was one of the Seven Wonders of the Ancient World.