Carl Sagan's novel 'The Dragons of EDEN' is a Pulitzer Prize-winning book that explores the evolution of human intelligence. The title refers to the mythical creatures that are said to have guarded the Garden of EDEN. The crossword solution for the term 'Sagan's 'The Dragons of EDEN'' is EDEN, which is a four-letter word. EDEN is a biblical reference to the Garden of EDEN, which is the location where Adam and Eve lived before they were expelled from paradise.