The capital city of the Rhone is Lyons, a five-letter word. Lyons is located in the Auvergne-Rhône-Alpes region of southeastern France and is the second-largest metropolitan area in the country. It is known for its historical and architectural landmarks, including the Basilica of Notre-Dame de Fourvière, the Gothic Saint Jean Cathedral, and the Renaissance Palais des Papes. The city is also home to many museums, galleries, and other cultural attractions. Lyons is an important economic center, with a strong focus on finance, technology, and tourism.