The term 'responsibility of office' can be summarized as the DUTY of an individual to fulfill their obligations in a professional capacity. This includes being accountable for their actions, adhering to the rules and regulations of the organization they are employed by, and providing quality service to their customers or clients. The four letter word associated with this term is 'DUTY', which implies that the individual must take on the responsibility of fulfilling their obligations in order to be successful in their role.