The term 'Reason for Hand-Wringing' can be summarized as a situation that causes distress or worry, with the crossword solution being 'WOE'. WOE is an expression of grief or sorrow, and is often used to describe a feeling of deep distress or misery. It is usually used to refer to a situation that is causing someone to feel overwhelmed or helpless. In this context, it is used to describe a situation that is causing someone to feel anxious or worried.