The answer to the crossword for the term 'OPPOSITE OF PALEO' is NEO, which stands for Neolithic. Neolithic is a period of time in human history that began around 10, 000 BCE and ended around 3, 000 BCE. It was characterized by the development of agriculture, animal husbandry, and the use of stone tools. This period of time is the opposite of the Paleolithic period, which preceded it and was characterized by the use of stone tools and hunting and gathering.