The crossword solution for the term 'ONE CAPLET, PERHAPS' is 'DOSE'. A DOSE is a measured quantity of medication that is taken at any one time. It is usually measured in milligrams (mg) or milliliters (ml). A caplet is a type of pill or tablet that is designed to be swallowed whole. It is often used to deliver medications in a single DOSE, such as one caplet per day. Therefore, the answer to the crossword clue 'ONE CAPLET, PERHAPS' is 'DOSE'.