Sciatica is a form of neuralgia of the hip and thigh, which is caused by compression of the sciatic nerve. It is characterized by pain that radiates from the lower back down the leg, often accompanied by numbness, tingling, and muscle weakness. Sciatica can be caused by a variety of conditions, including herniated discs, spinal stenosis, and piriformis syndrome. Treatment for sciatica typically includes rest, physical therapy, medications, and in some cases, surgery.