The term 'Neighbor of West Virginia' can be answered by two crossword solutions: Ohio (4 letters) and Maryland (8 letters). Ohio is a Midwestern state located in the Great Lakes region of the United States. It is bordered by Lake Erie to the north, Pennsylvania to the east, West Virginia to the south, and Indiana to the west. Maryland is a state located in the Mid-Atlantic region of the United States. It is bordered by Pennsylvania to the north, Delaware to the east, Virginia to the south, and West Virginia to the west.