The term 'Narcotic Plant' refers to plants that contain substances with psychoactive properties. MANDRAKE (8 letters) is a plant native to the Mediterranean region, and its root has been used for centuries as a sedative and anesthetic. Datura (6 letters) is a genus of flowering plants found in many parts of the world, and its seeds and flowers have been used for medicinal and recreational purposes. Mandragora (10 letters) is a species of perennial herb native to the Mediterranean region, and its root has been used as a sedative and anesthetic. COCA (4 letters) is a shrub native to South America, and its leaves have been used to produce cocaine, a powerful stimulant.