The two crossword solutions for the term 'Motrin Alternative' are ANACIN (6 letters) and ALEVE (5 letters). ANACIN is an over-the-counter pain reliever and fever reducer that contains aspirin and caffeine. It was first introduced in 1916 and is still available today. ALEVE is a brand of naproxen sodium, a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It was first approved by the FDA in 1994 and is also still available today.