Main Streets are a type of street that is typically the most important and heavily trafficked in a city or town. They are usually the first streets laid out in a new settlement and are often the focal point of a community. The term 'Main Streets' can also refer to the commercial districts of a city or town, which are usually located on the main streets. The crossword solution for Main Streets is AVENUES, which is a type of street that runs perpendicular to the main streets and is usually lined with trees.