The term HOME OF THE UNIVERSITY OF NEVADA can be solved by the four-letter word RENO. Reno is a city in the U.S. state of Nevada, located in the northwestern part of the state. It is the county seat of Washoe County and is known as 'The Biggest Little City in the World'. Reno is home to the University of Nevada, Reno, which is the state's land-grant university and its primary research institution.