Holy Toledo is an exclamation of surprise or amazement, often used to express disbelief. The crossword solutions for the term are YOW (3 letters), WOW (3 letters), MAN (3 letters), GEE (3 letters), EGAD (4 letters), WOWIE (5 letters), ZOWIE (5 letters), YIPE (4 letters), EGADS (5 letters), MYGOD (5 letters), GADZOOKS (8 letters), and GREATSCOTT (10 letters). These words are all interjections that are used to express surprise, shock, or excitement.