The term 'HOLY SPOT' can be defined by two crossword solutions: SHRINE (6 letters) and SANCTUM (7 letters). A SHRINE is a holy or sacred place dedicated to a specific deity, ancestor, hero, martyr, saint, or similar figure of awe and respect. It is usually marked by a structure or other landmark such as a statue, building, or a grove of trees. A sanctum is a place of refuge or safety, a private and sacred space. It is often used to refer to a place of worship or a temple.