Hilo is a major port city located on the Big Island of Hawaii. It is the largest settlement and census-designated place in Hawaii County, with a population of 43, 263 as of the 2010 census. Hilo is the county seat of Hawaii County and is situated in the South Hilo District. The city is home to the University of Hawaii at Hilo and is the second-largest city in the state after Honolulu. Hilo Harbor is a natural harbor located on the east side of the city, providing a safe haven for ships and boats.