The term 'First Name in Daytime TV' can be answered with four different names: OPRAH, Rosie, Ellen, and Regis. OPRAH Winfrey is an American media executive, talk show host, actress, producer, and philanthropist. She is best known for her talk show, The OPRAH Winfrey Show, which was the highest-rated television program of its kind in history. Rosie O'Donnell is an American comedian, actress, author, and television personality. She is best known for her talk show, The Rosie O'Donnell Show, which won multiple Emmy Awards. Ellen DeGeneres is an American comedian, television host, actress, writer, and producer. She is best known for her talk show, The Ellen DeGeneres Show, which has won multiple Emmy Awards. Regis Philbin is an American media personality, actor, and singer, best known for hosting a variety of talk shows and game shows, including Live! with Regis and Kelly, Who Wants to Be a Millionaire?, and America's Got Talent.