The term 'Enemies of the Iroquois' refers to three Native American tribes: the Erie, Eries, and Ottawas. The Erie were a tribe of Native Americans who lived in the Great Lakes region of North America. The Eries were a sub-tribe of the Erie. The Ottawas were a tribe of Native Americans who lived in the Great Lakes region and the northern Midwest. All three of these tribes were enemies of the Iroquois, a powerful confederacy of Native American tribes located in what is now upstate New York.