The term DES MOINES (6 letters) is the capital of the U.S. state of Iowa. It is located in the central part of the state, along the Des Moines River. The city has a population of over 200, 000 and is the most populous city in Iowa. Des Moines is home to many businesses, including insurance companies, financial services, and publishing companies. It is also a major cultural center, with a vibrant arts scene and numerous festivals and events.