The two crossword solutions for the term CITY SOUTHEAST OF ROME are NAPLES (6 letters) and Utica (5 letters). NAPLES is a city in southwestern Italy, located on the Gulf of NAPLES and is the capital of the Campania region. It is the third-largest city in Italy and is one of the oldest continuously inhabited cities in the world. Utica is a city in Central New York, located on the Mohawk River. It was an important city in the Roman Empire and was the first major settlement in the United States after the Revolutionary War.