The crossword solution for the term CITY ON THE SIERRA NEVADA is Reno, a four letter word. Reno is a city in the U.S. state of Nevada, located in the western part of the state on the eastern slope of the Sierra Nevada mountain range. It is the most populous city in Northern Nevada and is known as 'The Biggest Little City in the World'. Reno is also a popular tourist destination, known for its casinos, entertainment, and outdoor activities.