Iowa is a city located on the Mississippi River in the U.S. state of Iowa. Alton is a city located on the Mississippi River in the U.S. state of Illinois. Yazoo is a city located on the Mississippi River in the U.S. state of Mississippi. DELTA is a city located on the Mississippi River in the U.S. state of Louisiana. All four cities are situated along the banks of the Mississippi River, which is the second longest river in the United States.