The term CITY ON BISCAYNE BAY can be solved by two crossword solutions: Miami (5 letters) and Osaka (5 letters). Miami is a major port city on the Atlantic coast of south Florida in the United States. It is the most populous city in Florida and the 8th most populous city in the United States. It is located on the Biscayne Bay, which is a lagoon that is separated from the Atlantic Ocean by the barrier islands of Miami Beach and South Beach. Osaka is a large port city in the Kansai region of Japan. It is the third largest city in Japan and the second largest metropolitan area in the country. It is located on Osaka Bay, which is part of the larger Seto Inland Sea, and is connected to the Pacific Ocean by the Kii Channel.