The City of Tuscany is a region in central Italy, and the city of Siena is one of its most famous cities. Located in the heart of Tuscany, Siena is known for its medieval architecture, art, and culture. It is also home to the Palio di Siena, an annual horse race that has been held since the Middle Ages. Siena is a popular tourist destination, and its historic center is a UNESCO World Heritage Site.