The city of Assisi, located in central Italy, is a popular tourist destination due to its historical significance. It is the birthplace of St. Francis, the patron saint of Italy, and is home to several churches and monasteries. Ostia, also located in central Italy, is an ancient port city that was once the main port of Rome. It is now a popular beach resort and archaeological site. Both cities are located in the region of Umbria, which is known for its rolling hills, vineyards, and olive groves.