Messina is a city in Sicily with a population of over 250, 000 people. It is the third largest city in Sicily and is located on the northeast coast of the island. Enna is another city in Sicily, located in the center of the island. It is the highest city in Sicily and has a population of around 25, 000 people. Both cities are popular tourist destinations and offer a variety of attractions, including historical sites, beaches, and cultural activities.